GO Ahead Eagles opened their UEFA Europa League league-stage campaign with a 0–1 defeat to FCSB on Thursday, 25 September 2025. The match, played at a neutral venue, kicked off at 16:45 UTC and was officiated by Estonian referee Kristo Tohver. The only goal of the game arrived before the interval, with the visitors taking a 1–0 lead into half-time, a margin they defended through the second half to secure all three points on Matchday 1.

For FCSB, the victory was a vital start to their European c...