Lecce fell to a 1–2 home defeat against Cagliari on Friday, 19 September 2025, in Serie A Matchday 4. The match at the Stadio Via del Mare kicked off at 18:45 UTC under the charge of referee Luca Zufferli. The scoreline was level at 1–1 by half-time, but Cagliari pulled ahead after the break to claim all three points.

At this stage of the 2025–26 season, the result was a significant early blow for Lecce, who were still searching for their first win of the campaign. A home loss to a direct rival...