Genoa suffered a heavy defeat at home on Monday, 29 September 2025, falling 0–3 to Lazio in a Serie A Matchday 5 clash at the Stadio Luigi Ferraris. The match kicked off at 18:45 UTC under the supervision of referee Giovanni Ayroldi. By the half-time whistle, Lazio had already built a commanding 0–2 lead, leaving Genoa with a mountain to climb in the second period.

For Genoa, this was a sobering result at the very start of the 2025–26 campaign. Sitting in the bottom half of the tabl...