Newcastle suffered a 2–1 defeat at home to Arsenal on Sunday, 28 September 2025, in a Premier League Matchday 6 fixture that kicked off at 15:30 UTC. The match, officiated by Australian referee Jarred Gillett, saw Newcastle lead 1–0 at half-time before Arsenal turned the game around after the break. The result handed Arsenal three valuable points at St. James' Park and inflicted a damaging home loss on Newcastle in the early stages of the 2025–26 campaign.

For Newcastle, this defeat was a signi...