St. Louis City fell to a 4-2 defeat against Orlando City SC at CITYPARK on Thursday, 26 June 2025, in a Major League Soccer Matchday 19 fixture that kicked off at 00:30 UTC. The match, officiated by referee Guido Gonzales Jr of the USA, ended with a high-scoring 2-3 scoreline at half-time before Orlando added a fourth goal after the break to secure the victory on the road.

For St. Louis City, this home loss was a significant setback in their 2025 campaign. The defeat left the club searching for...