Santos Laguna opened the Liga MX 2025 season with a commanding 3–0 victory over U.N.A.M. - Pumas on Sunday, 13 July 2025. The match, which kicked off at 01:00 UTC on Matchday 1, was officiated by referee Yonatan Peinado Aguirre of Mexico. Santos Laguna held a 1–0 lead at half-time before adding two more goals in the second half to seal a comprehensive win on home soil.

For Santos Laguna, this result provided the perfect start to their Apertura campaign, laying down an early marker in the title ...