Puebla opened their Liga MX 2025 campaign with a 2–3 defeat to Atlas on Saturday, 12 July 2025, at a venue not recorded. The match, which kicked off at 01:00 UTC on Matchday 1, saw the sides level at 1–1 at half-time. Mario Terrazas Chavez of Mexico served as the referee.

For Puebla, the loss at home on the opening weekend was a damaging start to the season. Dropping points at the Estadio Cuauhtémoc so early placed immediate pressure on the squad to recover ground in the Apertura standings. Atl...