Mazatlán opened their Liga MX 2025 campaign with a 1–2 defeat to FC Juarez on Saturday, 10 January 2026, at the Estadio Mazatlán. Kickoff was at 01:00 UTC with Ivan Antonio Lopez Sanchez of Mexico officiating. The match was Matchday 1 of the Clausura tournament, and the visitors took a 1–2 lead into the half-time interval.

For Mazatlán, losing their home opener was a damaging start to the Clausura. The club entered the season aiming to climb away from the...