Cruz Azul suffered a 2–3 defeat at home to U.N.A.M. - Pumas on Sunday, 9 November 2025, in a Liga MX Matchday 17 clash that kicked off at 03:05 UTC. Referee Fernando Hernandez of Mexico oversaw the fixture, which saw the hosts go into the break leading 2–1 before Pumas mounted a second-half comeback to take all three points.

For Cruz Azul, this home loss was a damaging blow at the business end of the regular season. Sitting inside the playoff places at the time, dropping points at the Estadio C...