Cruz Azul made an early statement in the Liga MX 2025 season by defeating Atletico San Luis 2-1 on Tuesday, 12 August 2025, at a venue not specified. The match was played on Matchday 4 of the competition, kicking off at 03:05 UTC under the control of referee Vicente Jassiel Reynoso Arce of Mexico. The teams went into the break level at 0-0, but Cruz Azul found the goals needed in the second half to take all three points on the road.

For Cruz Azul, this away victory at the Alfonso Lastras Ramire...