Southampton fell to a 2–0 defeat against Preston North End at St Mary’s on Saturday, 1 November 2025, in a Championship Matchday 13 fixture that kicked off at 15:00 UTC. Referee Matt Donohue officiated the contest, which saw the visitors take a 1–0 lead into half-time before adding a second after the break. The result handed Southampton a damaging home loss in the second tier.

For Southampton, the defeat represented a setback in their push for an immediate return to the Premier League. Sitting ...