Portsmouth suffered a 2–0 defeat to Sheffield Wednesday at Fratton Park on Saturday, 20 September 2025, in a Championship Matchday 6 fixture that kicked off at 14:00 UTC. Referee Ruebyn Ricardo, from England, oversaw the contest, which saw the visitors take a 1–0 lead into half-time before adding a second goal after the break.

For Portsmouth, this loss represented a difficult early-season setback at home. At Matchday 6 of the Championship campaign, dropping points in front of their own supporte...